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AD mostly affects those over 65 years of age, however, people in their late forties can develop the prodromal stage of AD- mild cognitive impairment (MCI)

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Dapagliflozin reduced the primary composite outcome (sustained 50% eGFR decline, ESKD, or death from renal or cardiovascular causes) by 39% compared to placebo [47]

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The half-life of cagrilintide is 159-195 hours (approximately 6.6 to 8.1 days) making it suitable for once weekly subcutaneous administration [5]

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